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What is an example of a helix breaker?

What is an example of a helix breaker?

  • Helix breakers refer to things that disrupt the alpha helical secondary structure. Things that don't or can't adhere to the geometry required of an alpha helix will disrupt or "break" the helix. Proline is the best example of helix breaker, though Glycine is often categorized as such. , Computational Biologist!

What are some examples of helix breakers in amino acids?

  • Those are within the amino acid itself. Helix breakers refer to things that disrupt the alpha helical secondary structure. Things that don't or can't adhere to the geometry required of an alpha helix will disrupt or "break" the helix. Proline is the best example of helix breaker, though Glycine is often categorized as such.

Why is proline used as a helix breaker?

  • The source of proline role as a helix breaker comes from side chain constraints and sterics: In proline, the nitrogen atom is a part of a rigid side chain ring and rotation about the N?C (alpha) bond is not possible. Why does glycine destabilize alpha helix?

What is an example of a helix breaker?What is an example of a helix breaker?

Helix breakers refer to things that disrupt the alpha helical secondary structure. Things that don't or can't adhere to the geometry required of an alpha helix will disrupt or "break" the helix. Proline is the best example of helix breaker, though Glycine is often categorized as such. , Computational Biologist!

image-What is an example of a helix breaker?
image-What is an example of a helix breaker?
Related

Why are glycine and proline called 'helix breakers'?Why are glycine and proline called 'helix breakers'?

Proline and glycine are sometimes known as "helix breakers" because they disrupt the regularity of the α helical backbone conformation; however, both have unusual conformational abilities and are commonly found in turns.

Related

What can break an alpha helix?What can break an alpha helix?

Things that don't or can't adhere to the geometry required of an alpha helix will disrupt or "break" the helix. Proline is the best example of helix breaker, though Glycine is often categorized as such.

Related

What are some examples of helix breakers in amino acids?What are some examples of helix breakers in amino acids?

Those are within the amino acid itself. Helix breakers refer to things that disrupt the alpha helical secondary structure. Things that don't or can't adhere to the geometry required of an alpha helix will disrupt or "break" the helix. Proline is the best example of helix breaker, though Glycine is often categorized as such.

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